Sjögren’s Syndrome by Wan-Fai Ng

By Wan-Fai Ng

Basic Sjogren's syndrome is a rheumatic disorder affecting round 0.1-0.2% of the grownup girl inhabitants and leading to major incapacity with out enough remedy. prognosis is usually not on time and advised treatments will not be optimum, and a multidisciplinary method together with rheumatologists, ophthalmologists, oral drugs physicians, and others is necessary to sufferer administration.
This quantity summarises present realizing of the pathogenesis of the affliction, together with advances within the genetics of Sjogren's syndrome. Chapters hide disorder mechanisms, medical prognosis and overview, secondary Sjogren's syndrome, the function of laboratory investigations, and imaging. A therapy-based part covers topical oral and ocular remedies, and the function of steroids and biologics also are addressed.
Sjogren's Syndrome is a pragmatic, concise pocketbook that includes precis tables, key issues, and illustrations displaying very important mechanisms of affliction and pathways of care. The publication can be of curiosity to trainees in rheumatology, ophthalmology and oral medicine/surgery, expert practitioners and therapists keen on the care of sufferers with Sjogren's syndrome, and first care physicians, dentists, and different experts resembling Ent physicians.

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Extra resources for Sjögren’s Syndrome

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17 Management Guidelines on the management of pSS are currently under development by the British Society for Rheumatology and the EULAR SS study groups. The following recommendations are based on a combination of the experience of the authors, expert consensus, and reported studies. 6). • Provide advice on good eye care. • Encourage regular optician review. • Advise on tear substitutes. • Advise on lid care (see the explanation of meibomian gland dysfunction below). Replacement of tear volume palliates dry eye symptoms and may improve ocular surface disease.

Many different tools are available, some of which can be performed with specialist ophthalmological instruments or expertise. • Severity of ocular symptoms do not always correlate with the severity of objective findings. • Treatments should be tailored to the patient’s needs, severity of dry eye, and the symptoms. • A hierarchical treatment regime gauged upon the severity of dry eye symptoms and signs has been proposed by the dry eye workshop consisting of a combination of environmental optimization, tear supplementation, tear retention, tear stimulation, anti-inflammatories, and biological tear substitutes.

Caries occurs in an acidogenic oral environment; periodontal disease in a more alkaline milieu. In our experience, periodontal disease is not increased in SS patients. Probably, when the oral hygiene is insufficient, progressive carious destruction is a much quicker process than periodontal decay and will have resulted in loss of teeth before periodontal decay has resulted in serious clinical signs. How to assess oral features of Sjögren’s syndrome Collection of saliva It may sound strange, but the single most constant feature of saliva is its variability.

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